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原著論文2021年

July 21, 2021

    1.  Glyoxalase 1 and protein kinase Cλ as potential therapeutic targets for late-stage breast cancer
      Motomura H, Ozaki A, Tamori S, Onaga C, Nozaki Y, Waki Y, Takasawa R, Yoshizawa K, Mano Y, Sato T, Sasaki K, Ishiguro H, Miyagi Y, Nagashima Y, Yamamoto K, Sato K, Hanawa T, Tanuma SI, Ohno S, Akimoto K
      Oncol Lett., 2021, vol.22(No.1), p.547
    2.  GLO 1 and PKCλ regulate ALDH1-positive breast cancer stem cell survival
      Motomura H, Tamori S, Yatani M, Namiki A, Onaga C, Ozaki A, Takasawa R, Mano Y, Sato T, Hara Y, Sato K, Yuyun X, Harada Y, Hanawa T, Tanuma S, Sasaki K, Ohno S, Akimoto K
      Anticancer Res, 2021, vol41(No12), p.5959-5971
    3. Visualization of stem cell activity in pancreatic cancer expansion by direct lineage tracing with live imaging
      Maruno T, Fukuda A, Goto N, Tsuda M, Ikuta K, Hiramatsu Y, Ogawa S, Nakanishi Y, Yamaga Y, Yoshioka T, Takaori K, Uemoto S, Saur D, Chiba T, Seno H
      eLife, 2021, 10, p.e55117
    4. The role of the SWI/SNF chromatin remodeling complex in pancreatic ductal adenocarcinoma
      Tsuda M, Fukuda A, Kawai M, Araki O, Seno H
      Cancer Sci, 2021, 112(2), p.490-497
    5. Brg1 is required to maintain colorectal cancer stem cells
      Yoshikawa T, Fukuda A, Omatsu M, Namikawa M, Sono M, Fukunaga Y, Masuda T, Araki O, Nagao M, Ogawa S, Masuo K, Goto N, Hiramatsu Y, Muta Y, Tsuda M, Maruno T, Nakanishi Y, Kawada K, Takaishi S, Seno H
      J Pathol, 2021, 255(3), p.257-269
    6. SNAIL2 contributes to tumorigenicity and chemotherapy resistance in pancreatic cancer by regulating IGFBP2
      Masuo K, Chen R, Yogo A, Sugiyama A, Fukuda A, Masui T, Uemoto S, Seno H, Takaishi S
      Cancer Sci, 2021, 112(12), p.4987-4999
    7. Itraconazole Increases Resolvin E3 Concentration and 12/15-lipoxygenase Inhibitor Attenuates Itraconazole Cytotoxicity in Cervical Cancer Cells
      Isono R, Tsubamoto H, Inoue K, Ueda T, Takimoto Y, Sakata K, Shinohara M, Shibahara H
      Anticancer Res, 2021, 41(9), p.4271-4276
    8.  Mitochondrial matrix protein C14orf159 attenuates colorectal cancer metastasis by suppressing Wnt/β-catenin signalling.
      Ohshima K, Oi R, Okuzaki D, Motooka D, Shinohara M, Nojima S, Morii E
      Br J Cancer., 2021, 125(12), p.1699-1711
    9. On-tissue polysulfide visualization by surface-enhanced Raman spectroscopy benefits patients with ovarian cancer to predict post-operative chemosensitivity
      Honda K, Hishiki T, Yamamoto S, Yamamoto T, Miura N, Kubo A, Itoh M, Chen WY, Takano M, Yoshikawa T, Kasamatsu T, Sonoda S, Yoshizawa H, Nakamura S, Itai Y,  Shiota M, Koike D, Naya M, Hayakawa N, Naito Y, Matsuura T, Iwaisako K, Masui T, Uemoto S, Nagashima K, Hashimoto Y, Sakuma T, Matsubara O, Huang W, Ida T, Akaike T, Masugi Y, Sakamoto M, Kato T, Ino Y, Yoshida H, Tsuda H, Hiraoka N, Kabe Y, Suematsu M
      Redox Biology, 2021, vol 41, p.101926
    10. Glycyrrhizin Derivatives Suppress Cancer Chemoresistance by Inhibiting Progesterone Receptor Membrane Component 1
      Kabe Y, Koike I, Yamamoto T, Hirai M,  Kanai A, Furuhata R , Tsugawa H,  Sugase E, Hanadate K, Yoshikawa N, Hayashi H, Noda H, M, Uchiyama S, Yamazaki H, Tanaka H,  Kobayashi T, Handa H, Suematsu M
      Cancers, 2021, vol. 13, p.3265
    11. Possible Therapeutic Strategy Involving the Purine Synthesis Pathway Regulated by ITK in Tongue Squamous Cell Carcinoma
      Onidani K, Miura N, Sugiura Y, Abe Y, Watabe Y, Kakuya T, Mori, T, Yoshimoto S, Adachi J, Kiyoi T, Kabe Y,  Suematsu M, Tomonaga T, Shibahara T, Honda, K
      Cancers, 2021, vol. 13, p.3333
    12.  POLYseq: A poly(β-amino ester)-based vector for multifunctional cellular barcoding
      Dunn A, Cai Y, Iwasawa K, Kimura M, Takebe T
      Stem Cell Reports, 2021, 16(9), p.2149-2158
    13. Intravital imaging identifies the VEGF-TXA2 axis as a critical promoter of PGE2 secretion from tumor cells and immune evasion
      Konishi Y, Ichise H, Watabe T, Oki C, Tsukiji S, Hamazaki Y, Murakawa Y, Takaori-Kondo A, Terai K, Matsuda M
      Cancer Res, 2021, 81(15), p.4124-4132
    14.  Two-photon AMPK and ATP imaging reveals the bias between rods and cones in glycolysis utility, 
      Jiazhou He,Masamichi Yamamoto,Kenta Sumiyama,Yumi Konagaya,Kenta Terai,Michiyuki Matsuda,Shinya Sato
      The FASEB Journal, 2021, 35(9), p.e21880
    15.  Redundant roles of EGFR ligands in the ERK activation waves during collective cell migrationShuhao Lin, Daiki Hirayama, Gembu Maryu, Kimiya Matsuda, Naoya Hino, Eriko Deguchi, Kazuhiro Aoki, Ryo Iwamoto, Kenta Terai, Michiyuki Matsuda
      Life Sci Alliance, 2021, 5(1), p.e202101206
    16. Gut bacteria identified in colorectal cancer patients promote tumourigenesis via butyrate secretion
      Shintaro Okumura, Yusuke Konishi, Megumi Narukawa, Yuki Sugiura, Shin Yoshimoto, Yuriko Arai, Shintaro Sato, Yasuo Yoshida, Shunya Tsuji, Ken Uemura, Masahiro Wakita, Tatsuyuki Matsudaira, Tomonori Matsumoto, Shimpei Kawamoto, Akiko Takahashi, Yoshiro Itatani, Hiroaki Miki, Manabu Takamatsu, Kazutaka Obama, Kengo Takeuchi, Makoto Suematsu, Naoko Ohtani, Yosuke Fukunaga, Masashi Ueno, Yoshiharu Sakai, Satoshi Nagayama, and Eiji Hara
      Nature Communications, 2021, 12, p.5674
    17. FGF21 induced by the ASK1-p38 pathway promotes mechanical cell competition by attracting cells
      Ogawa, M., Kawarazaki, Y., Fujita, Y., Naguro, I. and Ichijo, H
      Curr. Biol., 2021, vol. 31(No. 5), p.1048-1057
    18. Cells recognize osmotic stress through liquid-liquid phase separation lubricated with poly (ADP-ribose)
      Watanabe, K., Morishita, K., Zhou, X., Shiizaki, S., Uchiyma, Y., Koike, M., Naguro, I., Ichijo, H
      Nat. Commun., 2021, vol. 12(No. 1), p.1353
    19. ASK1 suppresses NK cell-mediated intravascular tumor cell clearance in lung metastasis
      Fujimoto, M., Kamiyama, M., Fuse, K., Ryuno, H., Odawara, T., Furukawa, N., Yoshimatsu, Y., Watabe, T., Michaela, P.-M. Veronika, S., Tahara, H., Hayakawa, Y., Sato, T., Takeda, K., Naguro, I. and Ichijo, H
      Cancer Sci., 2021, vol. 112(No. 4), p.1633-1643
    20. The mitochondrial CA2+ uptake regulator, MICU1 is involved in cold stress-induced ferroptosis
      Nakamura, T., Ogawa, M., Kojima, K., Takayanagi, S., Ishihara, S., Hattori, K., Naguro, I. and Ichijo, H
      EMBO Rep., 2021, vol. 5(No. 5), p.e51532
    21. ASKA technology-based pull-down method reveals a suppressive effect of ASK1 on the inflammatory NOD-RIPK2 pathway in brown adipocytes
      Takayanagi, S., Watanabe, K., Maruyama, T., Ogawa, M., Morishita, K., Soga, M., Hatta, T., Natsume, T., Hirano, T., Kagechika, H., Hattori, K., Naguro, I. and Ichijo, H
      Sci. Rep., 2021, 11(1), p.22009
    22. Pericentromeric noncoding RNA changes DNA binding of CTCF and inflammatory gene expression in senescence and cancer
      Miyata, K., Imai, Y., Hori, S., Nishio, M., Loo, T.M., Okada, R., Yang, L., Nakadai, T., Maruyama, R., Fujii, R., Ueda, K., Jiang, Li., Zheng, H., Toyokuni, S., Sakata, T., Shirahige, K., Kojima, R., Nakayama, M., Oshima, M., Nagayama, S., Seimiya, H., Hirota, T., Saya, H., Hara, E. & *Takahashi, A
      Proc. Natl. Acad. Sci. U.S.A., 2021, 118(35), p.e2025647118
    23. Gut bacteria identified in colorectal cancer patients promote tumourigenesis via butyrate secretion
      Okumura, S., Konishi, Y., Narukawa, M., Sugiura, Y, Yoshimoto, S., Arai, Y., Sato, S., Yoshida, Y., Tsuji, S., Uemura, K., Wakita, M., Matsudaira, T., Matsumoto, T., Kawamoto, S., Takahashi, A., Itatani, Y., Miki, H., Takamatsu, M, Obama, K., Takeuchi, K., Suematsu, M., Ohtani, N., Fukunaga, Y., Ueno, M., Sakai, Y., Nagayama, S. and Hara, E.
      Nature Communications, 2021, 12(1), p.5674
    24. Characterization of morphological alterations in micropapillary adenocarcinoma of the lung using an established cell line
      Sonoda, D., Kamizaki, K., Matsuo, Y., Aruga, K., Mikubo, M., Yamashita, K., Nishita, M., Minami, Y., Satoh, Y
      Oncol. Rep., 2021, 47(1), p.19
    25.  The CD44/COL17A1 Pathway Promotes the Formation of Multilayered, Transformed Epithelia
      Kozawa,K., Sekai, M., Ohba, K., Ito, S., Sako, H., Maruyama, T., Kakeno, M., Shirai, T., Kuromiya, K., Kamasaki, T., Kohashi, K., Tanaka, S., Ishikawa, S., Sato, N., Asano, S., Suzuki, H., Tanimura, N., Mukai, Y., Gotoh, N., Tanino, M., Tanaka, S., Natsuga, K., Soga, T., Nakamura, T., Yabuta, Y., Saitou, M., Ito, T., Matsuura, K., Tsunoda, M., Kikumori, T., Iida, T., Mizutani, Y., Miyai, Y., Kaibuchi, K., Enomoto, A., and Fujita, Y
      Current Biology, 2021, 31(14), p.3086-2097
    26.  Sequential Oncogenic Mutations Influence Cell Competition
      Kohashi, K., Mori, Y., Narumi, R., Kozawa, K., Kamasaki, T., Ishikawa, S., Kajita, M., Kobayashi, R., Tamori, Y., and Fujita, Y
      Current Biology, 2021, 31(18), p.3984-3995
    27. FBP17-mediated finger-like membrane protrusions in cell competition between normal and RasV12-transformed cells
      Kamasaki, T., Miyazaki, Y., Ishikawa, S., Hoshiba, K., Kuromiya, K., Tanimura, N., Mori, Y., Tsutsumi, M., Nemoto, T., Uehara, R., Suetsugu, S., Itoh, T., and Fujita, Y
      iScience, 2021, 24(9), p.102994
    28. JNK and Yorkie drive tumor malignancy by inducing L-amino acid transporter 1 in Drosophila
      Bojie Cong, Mai Nakamura, Yukari Sando, Takefumi Kondo, Shizue Ohsawa, Tatsushi Igaki,  PLoS Genetics, 2021, 17(11), p.e1009893
    29. High SLC20A1 Expression Is Associated With Poor Prognoses in Claudin-low and Basal-like Breast Cancers
      Onaga C, Tamori S, Motomura H, Ozaki A, Matsuda C, Matsuoka I, Fujita T, Nozaki Y, Hara Y, Kawano Y, Harada Y, Sato T, Mano Y, Sato K, Akimoto K
      Anticancer Res, 2021, 41巻(1号), p.43-54
    30. De novo ATP1A3 variants cause polymicrogyriaSatoko Miyatake 他48名
      Science Advances, 2021, vol.7(No.13), p.eabd2368
    31. PTEN is required for the migration and invasion of Ras-transformed MDCK cells.Yan, L., Tsujita, K., Fujita, Y., and Ito, T
      FEBS Letters , 2021, 595(9), p.1303-1312
    32. FGF21 Induced by the ASK1-p38 Pathway Promotes Mechanical Cell Competition by Attracting Cells
      Ogawa Motoyuki、Kawarazaki Yosuke、Fujita Yasuyuki、Naguro Isao、Ichijo Hidenori
      Current Biology, 2021, vol.31, p.1048-1057. e5
    33. A common SNP risk variant MT1-MMP causative for Dupuytren’s disease has a specific defect in collagenolytic activity
      Itoh Yoshifumi、Ng Michael、Wiberg Akira、Inoue Katsuaki、Hirata Narumi、Paiva Katiucia Batista Silva、Ito Noriko、Dzobo Kim、Sato Nanami、Gifford Valentina、Fujita Yasuyuki、Inada Masaki、 Furniss Dominic
      Matrix Biology, 2021, vol.97, p.20-39
    34. Non-cell-autonomous migration of RasV12-transformed cells towards the basal side of surrounding normal cells
      Jebri Imen、Tsujita Kazuya、Fujita Yasuyuki、Itoh Toshiki
      Biochemical and Biophysical Research Communications, 2021, vol.543, p.15-22
    35. A dual promoter system to monitor IFN-γ signaling in vivo at single-cell resolution
      Tanaka, T. Konishi, Y. Ichise, H. Tsukiji, S. Matsuda, M. Terai, K
      Cell Struct Funct, 2021, 46(2), p.103-111
    36. racheal motile cilia in mice require CAMSAP3 for the formation of central microtubule pair and coordinated beating
      Saito H, Matsukawa-Usami F, Fujimori T, Kimura T, Ide T, Yamamoto T, Shibata T, Onoue K, Okayama S, Yonemura S, Misaki K, Soba Y, Kakui Y, Sato M, Toya M, Takeichi.
      Mol Biol Cell., 2021, 32(20), p.ar12
    37.  RanGTP and the actin cytoskeleton keep paternal and maternal chromosomes apart during fertilization
      Mori M, Yao T, Mishina T, Endoh H, Tanaka M, Yonezawa N, Shimamoto Y, Yonemura S, Yamagata K, Kitajima TS, Ikawa M
      J Cell Biol. , 2021, 220(10), p.e202012001
    38. MEK inhibition suppresses metastatic progression of KRAS-mutated gastric cancer
      Yamasaki J, Hirata Y, Otsuki Y, Suina K, Saito Y, Masuda K, Okazaki S, Ishimoto T, Saya H, Nagano O
      Cancer Sci, 2021, 113(3), p.916-925
    39.  Homeostatic membrane tension constrains cancer cell dissemination by counteracting BAR protein assembly
      Tsujita, K., Satow, R., Asada, S., Nakamura, Y., Arnes, L., Sako, K., Fujita, Y., Fukami, K., and Itoh, T
      Nature Communications, 2021, 12(1), p.5930
    40.  Epithelial cells remove precancerous cells by cell competition via MHC class I-LILRB3 interaction
      Ayukawa, S., Kamoshita, N., Nakayama, J., Teramoto, R., Pishesha, N., Ohba, K., Sato, N., Kozawa, K., Abe, H., Semba, K., Goda, N., Fujita, Y., Maruyama, T
      Nature Immunology, 2021, 22(11), p.1391-1402