研究成果

  • 原著論文

    Motomura H, Ozaki A, Tamori S, Onaga C, Nozaki Y, Waki Y, Takasawa R, Yoshizawa K, Mano Y, Sato T, Sasaki K, Ishiguro H, Miyagi Y, Nagashima Y, Yamamoto K, Sato K, Hanawa T, Tanuma SI, Ohno S, Akimoto K., Glyoxalase 1 and protein kinase Cλ as potential therapeutic targets for late-stage breast cancer. , Oncol Lett. , 2021, vol.22(No.1), p.547

    Motomura H, Tamori S, Yatani M, Namiki A, Onaga C, Ozaki A, Takasawa R, Mano Y, Sato T, Hara Y, Sato K, Yuyun X, Harada Y, Hanawa T, Tanuma S, Sasaki K, Ohno S, Akimoto K, GLO 1 and PKCλ regulate ALDH1-positive breast cancer stem cell survival. , Anticancer Res, 2021, vol41(No12), p.5959-5971

    Maruno T, Fukuda A, Goto N, Tsuda M, Ikuta K, Hiramatsu Y, Ogawa S, Nakanishi Y, Yamaga Y, Yoshioka T, Takaori K, Uemoto S, Saur D, Chiba T, Seno H., Visualization of stem cell activity in pancreatic cancer expansion by direct lineage tracing with live imaging., eLife, 2021, 10, p.e55117

    Tsuda M, Fukuda A, Kawai M, Araki O, Seno H., The role of the SWI/SNF chromatin remodeling complex in pancreatic ductal adenocarcinoma., Cancer Sci, 2021, 112(2), p.490-497

    Yoshikawa T, Fukuda A, Omatsu M, Namikawa M, Sono M, Fukunaga Y, Masuda T, Araki O, Nagao M, Ogawa S, Masuo K, Goto N, Hiramatsu Y, Muta Y, Tsuda M, Maruno T, Nakanishi Y, Kawada K, Takaishi S, Seno H., Brg1 is required to maintain colorectal cancer stem cells., J Pathol, 2021, 255(3), p.257-269

    Masuo K, Chen R, Yogo A, Sugiyama A, Fukuda A, Masui T, Uemoto S, Seno H, Takaishi S., SNAIL2 contributes to tumorigenicity and chemotherapy resistance in pancreatic cancer by regulating IGFBP2., Cancer Sci, 2021, 112(12), p.4987-4999

    Isono R, Tsubamoto H, Inoue K, Ueda T, Takimoto Y, Sakata K, Shinohara M, Shibahara H., Itraconazole Increases Resolvin E3 Concentration and 12/15-lipoxygenase Inhibitor Attenuates Itraconazole Cytotoxicity in Cervical Cancer Cells., Anticancer Res, 2021, 41(9), p.4271-4276

    Ohshima K, Oi R, Okuzaki D, Motooka D, Shinohara M, Nojima S, Morii E., Mitochondrial matrix protein C14orf159 attenuates colorectal cancer metastasis by suppressing Wnt/β-catenin signalling., Br J Cancer., 2021, 125(12), p.1699-1711

    Kazufumi Honda, Takako Hishiki, Sohei Yamamoto, Takehiro Yamamoto, Nami Miura, Akiko Kubo, Mai Itoh, Wei-Yu Chen, Masashi Takano, Tomoyuki Yoshikawa, Takahiro Kasamatsu, Shinichiro Sonoda, Hirotoshi Yoshizawa, Seigo Nakamura, Yuichiro Itai, Megumi Shiota, Daisuke Koike, Masayuki Naya, Noriyo Hayakawa, Yoshiko Naito, Tomomi Matsuura, Keiko Iwaisako, Toshihiko Masui, Shinji Uemoto, Kengo Nagashima, Yoshinori Hashimoto, Tomohiro Sakuma, Osamu Matsubara, Wilber Huang, Tomoaki Ida, Takaaki Akaike, Yohei Masugi, Michiie Sakamoto, Tomoyasu Kato, Yoshinori Ino, Hiroshi Yoshida, Hitoshi Tsuda, Nobuyoshi Hiraoka, Yasuaki Kabe, Makoto Suematsu, On-tissue polysulfide visualization by surface-enhanced Raman spectroscopy benefits patients with ovarian cancer to predict post-operative chemosensitivity, Redox Biology, 2021, vol 41, p.101926

    Kabe, Y.; Koike, I.; Yamamoto, T.; Hirai, M.; Kanai, A.; Furuhata, R.; Tsugawa, H.; Harada, E.; Sugase, K.; Hanadate, K.; Yoshikawa, N.; Hayashi, H.; Noda, M.; Uchiyama, S.; Yamazaki, H.; Tanaka, H.; Kobayashi, T.; Handa, H.; Suematsu, M., Glycyrrhizin Derivatives Suppress Cancer Chemoresistance by Inhibiting Progesterone Receptor Membrane Component 1, Cancers, 2021, vol. 13, p.3265

    Onidani, K.; Miura, N.; Sugiura, Y.; Abe, Y.; Watabe, Y.; Kakuya, T.; Mori, T.; Yoshimoto, S.; Adachi, J.; Kiyoi, T.; Kabe, Y.; Suematsu, M.; Tomonaga, T.; Shibahara, T.; Honda, K, Possible Therapeutic Strategy Involving the Purine Synthesis Pathway Regulated by ITK in Tongue Squamous Cell Carcinoma, Cancers, 2021, vol. 13, p.3333

    Dunn A, Cai Y, Iwasawa K, Kimura M, Takebe T
    , POLYseq: A poly(β-amino ester)-based vector for multifunctional cellular barcoding, Stem Cell Reports, 2021, 16(9), p.2149-2158

    Yoshinobu Konishi, Hiroshi Ichise, Tetsuya Watabe, Choji Oki, Shinya Tsukiji, Yoko Hamazaki, Yasuhiro Murakawa, Akifumi Takaori-Kondo, Kenta Terai, Michiyuki Matsuda, Intravital imaging identifies the VEGF-TXA2 axis as a critical promoter of PGE2 secretion from tumor cells and immune evasion, Cancer Res, 2021, 81(15), p.4124-4132

    Jiazhou He,Masamichi Yamamoto,Kenta Sumiyama,Yumi Konagaya,Kenta Terai,Michiyuki Matsuda,Shinya Sato, Two-photon AMPK and ATP imaging reveals the bias between rods and cones in glycolysis utility, The FASEB Journal, 2021, 35(9), p.e21880

    Shuhao Lin, Daiki Hirayama, Gembu Maryu, Kimiya Matsuda, Naoya Hino, Eriko Deguchi, Kazuhiro Aoki, Ryo Iwamoto, Kenta Terai, Michiyuki Matsuda, Redundant roles of EGFR ligands in the ERK activation waves during collective cell migration, Life Sci Alliance, 2021, 5(1), p.e202101206

    Shintaro Okumura, Yusuke Konishi, Megumi Narukawa, Yuki Sugiura, Shin Yoshimoto, Yuriko Arai, Shintaro Sato, Yasuo Yoshida, Shunya Tsuji, Ken Uemura, Masahiro Wakita, Tatsuyuki Matsudaira, Tomonori Matsumoto, Shimpei Kawamoto, Akiko Takahashi, Yoshiro Itatani, Hiroaki Miki, Manabu Takamatsu, Kazutaka Obama, Kengo Takeuchi, Makoto Suematsu, Naoko Ohtani, Yosuke Fukunaga, Masashi Ueno, Yoshiharu Sakai, Satoshi Nagayama, and Eiji Hara, Gut bacteria identified in colorectal cancer patients promote tumourigenesis via butyrate secretion., Nature Communications, 2021, 12, p.5674

    Ogawa, M., Kawarazaki, Y., Fujita, Y., Naguro, I. and Ichijo, H. , FGF21 induced by the ASK1-p38 pathway promotes mechanical cell competition by attracting cells., Curr. Biol., 2021, vol. 31(No. 5), p.1048-1057

    Watanabe, K., Morishita, K., Zhou, X., Shiizaki, S., Uchiyma, Y., Koike, M., Naguro, I., Ichijo, H. , Cells recognize osmotic stress through liquid-liquid phase separation lubricated with poly (ADP-ribose)., Nat. Commun., 2021, vol. 12(No. 1), p.1353

    Fujimoto, M., Kamiyama, M., Fuse, K., Ryuno, H., Odawara, T., Furukawa, N., Yoshimatsu, Y., Watabe, T., Michaela, P.-M. Veronika, S., Tahara, H., Hayakawa, Y., Sato, T., Takeda, K., Naguro, I. and Ichijo, H., ASK1 suppresses NK cell-mediated intravascular tumor cell clearance in lung metastasis., Cancer Sci., 2021, vol. 112(No. 4), p.1633-1643

    Nakamura, T., Ogawa, M., Kojima, K., Takayanagi, S., Ishihara, S., Hattori, K., Naguro, I. and Ichijo, H., The mitochondrial CA2+ uptake regulator, MICU1 is involved in cold stress-induced ferroptosis., EMBO Rep., 2021, vol. 5(No. 5), p.e51532

    Takayanagi, S., Watanabe, K., Maruyama, T., Ogawa, M., Morishita, K., Soga, M., Hatta, T., Natsume, T., Hirano, T., Kagechika, H., Hattori, K., Naguro, I. and Ichijo, H. , ASKA technology-based pull-down method reveals a suppressive effect of ASK1 on the inflammatory NOD-RIPK2 pathway in brown adipocytes., Sci. Rep., 2021, 11(1), p.22009

    Miyata, K., Imai, Y., Hori, S., Nishio, M., Loo, T.M., Okada, R., Yang, L., Nakadai, T., Maruyama, R., Fujii, R., Ueda, K., Jiang, Li., Zheng, H., Toyokuni, S., Sakata, T., Shirahige, K., Kojima, R., Nakayama, M., Oshima, M., Nagayama, S., Seimiya, H., Hirota, T., Saya, H., Hara, E. & *Takahashi, A., Pericentromeric noncoding RNA changes DNA binding of CTCF and inflammatory gene expression in senescence and cancer., Proc. Natl. Acad. Sci. U.S.A., 2021, 118(35), p.e2025647118

    Okumura, S., Konishi, Y., Narukawa, M., Sugiura, Y, Yoshimoto, S., Arai, Y., Sato, S., Yoshida, Y., Tsuji, S., Uemura, K., Wakita, M., Matsudaira, T., Matsumoto, T., Kawamoto, S., Takahashi, A., Itatani, Y., Miki, H., Takamatsu, M, Obama, K., Takeuchi, K., Suematsu, M., Ohtani, N., Fukunaga, Y., Ueno, M., Sakai, Y., Nagayama, S. and Hara, E. , Gut bacteria identified in colorectal cancer patients promote tumourigenesis via butyrate secretion., Nature Communications, 2021, 12(1), p.5674

    Sonoda, D., Kamizaki, K., Matsuo, Y., Aruga, K., Mikubo, M., Yamashita, K., Nishita, M., Minami, Y., Satoh, Y., Characterization of morphological alterations in micropapillary adenocarcinoma of the lung using an established cell line., Oncol. Rep., 2021, 47(1), p.19

    Kozawa,K., Sekai, M., Ohba, K., Ito, S., Sako, H., Maruyama, T., Kakeno, M., Shirai, T., Kuromiya, K., Kamasaki, T., Kohashi, K., Tanaka, S., Ishikawa, S., Sato, N., Asano, S., Suzuki, H., Tanimura, N., Mukai, Y., Gotoh, N., Tanino, M., Tanaka, S., Natsuga, K., Soga, T., Nakamura, T., Yabuta, Y., Saitou, M., Ito, T., Matsuura, K., Tsunoda, M., Kikumori, T., Iida, T., Mizutani, Y., Miyai, Y., Kaibuchi, K., Enomoto, A., and Fujita, Y., The CD44/COL17A1 Pathway Promotes the Formation of Multilayered, Transformed Epithelia., Current Biology, 2021, 31(14), p.3086-2097

    Kohashi, K., Mori, Y., Narumi, R., Kozawa, K., Kamasaki, T., Ishikawa, S., Kajita, M., Kobayashi, R., Tamori, Y., and Fujita, Y., Sequential Oncogenic Mutations Influence Cell Competition., Current Biology, 2021, 31(18), p.3984-3995

    Kamasaki, T., Miyazaki, Y., Ishikawa, S., Hoshiba, K., Kuromiya, K., Tanimura, N., Mori, Y., Tsutsumi, M., Nemoto, T., Uehara, R., Suetsugu, S., Itoh, T., and Fujita, Y., FBP17-mediated finger-like membrane protrusions in cell competition between normal and RasV12-transformed cells., iScience, 2021, 24(9), p.102994

    Bojie Cong, Mai Nakamura, Yukari Sando, Takefumi Kondo, Shizue Ohsawa, Tatsushi Igaki, JNK and Yorkie drive tumor malignancy by inducing L-amino acid transporter 1 in Drosophila, PLoS Genetics, 2021, 17(11), p.e1009893

    Onaga C, Tamori S, Motomura H, Ozaki A, Matsuda C, Matsuoka I, Fujita T, Nozaki Y, Hara Y, Kawano Y, Harada Y, Sato T, Mano Y, Sato K, Akimoto K., High SLC20A1 Expression Is Associated With Poor Prognoses in Claudin-low and Basal-like Breast Cancers., Anticancer Res, 2021, 41巻(1号), p.43-54

    Satoko Miyatake 他48名, De novo ATP1A3 variants cause polymicrogyria, Science Advances, 2021, vol.7(No.13), p.eabd2368

    Yan, L., Tsujita, K., Fujita, Y., and Ito, T., PTEN is required for the migration and invasion of Ras-transformed MDCK cells., FEBS Letters , 2021, 595(9), p.1303-1312

    Ogawa Motoyuki、Kawarazaki Yosuke、Fujita Yasuyuki、Naguro Isao、Ichijo Hidenori, FGF21 Induced by the ASK1-p38 Pathway Promotes Mechanical Cell Competition by Attracting Cells, Current Biology, 2021, vol.31, p.1048-1057. e5

    Itoh Yoshifumi、Ng Michael、Wiberg Akira、Inoue Katsuaki、Hirata Narumi、Paiva Katiucia Batista Silva、Ito Noriko、Dzobo Kim、Sato Nanami、Gifford Valentina、Fujita Yasuyuki、Inada Masaki、 Furniss Dominic, A common SNP risk variant MT1-MMP causative for Dupuytren’s disease has a specific defect in collagenolytic activity, Matrix Biology, 2021, vol.97, p.20-39

    Jebri Imen、Tsujita Kazuya、Fujita Yasuyuki、Itoh Toshiki, Non-cell-autonomous migration of RasV12-transformed cells towards the basal side of surrounding normal cells, Biochemical and Biophysical Research Communications, 2021, vol.543, p.15-22

    Tanaka, T. Konishi, Y. Ichise, H. Tsukiji, S. Matsuda, M. Terai, K., A dual promoter system to monitor IFN-γ signaling in vivo at single-cell resolution, Cell Struct Funct, 2021, 46(2), p.103-111

    Saito H, Matsukawa-Usami F, Fujimori T, Kimura T, Ide T, Yamamoto T, Shibata T, Onoue K, Okayama S, Yonemura S, Misaki K, Soba Y, Kakui Y, Sato M, Toya M, Takeichi., Tracheal motile cilia in mice require CAMSAP3 for the formation of central microtubule pair and coordinated beating., Mol Biol Cell., 2021, 32(20), p.ar12

    Mori M, Yao T, Mishina T, Endoh H, Tanaka M, Yonezawa N, Shimamoto Y, Yonemura S, Yamagata K, Kitajima TS, Ikawa M., RanGTP and the actin cytoskeleton keep paternal and maternal chromosomes apart during fertilization , J Cell Biol. , 2021, 220(10), p.e202012001

    Yamasaki J, Hirata Y, Otsuki Y, Suina K, Saito Y, Masuda K, Okazaki S, Ishimoto T, Saya H, Nagano O, MEK inhibition suppresses metastatic progression of KRAS-mutated gastric cancer., Cancer Sci, 2021, 113(3), p.916-925

    Tsujita, K., Satow, R., Asada, S., Nakamura, Y., Arnes, L., Sako, K., Fujita, Y., Fukami, K., and Itoh, T. , Homeostatic membrane tension constrains cancer cell dissemination by counteracting BAR protein assembly., Nature Communications, 2021, 12(1), p.5930

    Ayukawa, S., Kamoshita, N., Nakayama, J., Teramoto, R., Pishesha, N., Ohba, K., Sato, N., Kozawa, K., Abe, H., Semba, K., Goda, N., Fujita, Y., Maruyama, T. , Epithelial cells remove precancerous cells by cell competition via MHC class I-LILRB3 interaction, Nature Immunology, 2021, 22(11), p.1391-1402

  • 招待講演

    片岡圭亮, 成人 T 細胞白血病リンパ腫におけるゲノム異常の全体像, 第80回日本癌学会学術総会, 2021/10

    山本陽一朗, 先端的医療AI研究及び実績紹介, 東北大学Clinical AIアニュアルシンポジウム, 2021/03

    山本陽一朗, 発見的な機械学習によるがん研究と予後予測, 第3回日本メディカルAI学会学術集会, 2021/06

    山本陽一朗, 知識を紡ぐ医療 AI 技術, 第29回日本乳癌学会学術総会, 2021/07

    山本陽一朗, 未知なる知識をラーニングする〜根拠を紐解き、未来の医療を紡ぐ~, 第3回ナイスステップ講演会, 2021/07

    山本陽一朗, 医療AIの導入と活用のポイント, 第80回日本癌学会学術総会, 2021/10

    山本陽一朗, 泌尿器腫瘍とAI, 日本泌尿器腫瘍学会第7回学術集会, 2021/10

    Takanori Takebe, Liver organoids for sustainability, ISSCR digital/Stem Cells and Global Sustainability, 2021/02

    武部貴則, ヒューマン・オルガノイドを用いた薬理研究, 第94回日本薬理学会年会, 2021/03

    武部貴則, 「多検体由来ヒト幹細胞クローンを用いた肝臓オルガノイドのドナー間比較解析~ヒトiPS由来胚葉分化工程における観察的アプローチ」, 日本再生医療学会, 2021/03

    武部貴則, My Medicine −オルガノイドとストリート・メディカル研究, 第124回日本小児科学会学術集会, 2021/04

    武部貴則, 内分泌相互作用を加味した肝臓オルガノイド研究, 第94回日本内分泌学会学術総会, 2021/04

    Takanori Takebe, Engineering Organoids and Organs, Cell Symposia, 2021/04

    Takanori Takebe, HIRAMEKI conference at Spain,, Takeda Spain-sponsored WEB event, 2021/04

    武部貴則, Modeling hepato-biliary-pancreatic organogenesis towards therapy, 第18回幹細胞シンポジウム, 2021/05

    武部貴則, 肝臓におけるオルガノイド医学の展開, 第57回日本肝臓学会総会, 2021/06

    武部貴則, オルガノイド医療がもたらす未来, 第64回日本腎臓学会学術総会, 2021/06

    武部貴則, オルガノイド医療の可能性, 日本毒性学会, 2021/07

    武部貴則, 臓器再生への展望, 日本動物細胞工学学会, 2021/07

    Takanori Takebe, Using Stem Cell and Organoid Biology to Model Complex Human Development and Identify New Therapies, 2021 Virtual FASEB SRC “The Gastrointestinal Tract XIX Conference, 2021/08

    浦野泰照, ライブイメージングと最新化学に基づく新たながん医療技術の創製, 消化器領域seminar from Asahikawa, 2021/02

    Yasuteru Urano, Intraoperative Rapid Imaging of Tiny Tumors by Novel Fluorogenic Probes for Exopeptidases and Glycosidases, OIST and UT joint talk series for future science, 2021/03

    Yasuteru Urano, Intraoperative Rapid Imaging of Tiny Tumors by Novel Fluorogenic Probes for Exopeptidases and Glycosidases, Bioorthogonal and Bioresponsive Symposium 2021, 2021/06

    浦野泰照, ケミカルバイオロジーからケミカルメディシンへ ~臨床検体のバイオイメージングに基づく新がん医療技術の創製~, 第43回日本光医学・光生物学会, 2021/07

    浦野泰照, ライブイメージングと最新化学に基づく新たながん医療技術の創製, 第7回次世代を担う若手のためのレギュラトリーサイエンスフォーラム, 2021/10

    Yasuteru Urano, Mako Kamiya, Rapid cancer imaging by rationally designed fluorescence probes, 第80回日本癌学会学術総会, 2021/10

    浦野泰照, 蛍光ライブイメージングに基づく新たながん診断・治療技術の創製, 第61回日本核医学会学術総会, 2021/11
    原 英二, 細胞老化を標的としたがん治療の可能性, 第25回日本がん分子標的治療学会 , 2021/05

    原 英二, がんと老化における細胞老化の役割, 第53回日本結合組織学会, 2021/06

    Eiji Hara, Cellular senescence and cancer: a gut microbial connection, 39th Sapporo International Cancer Symposium , 2021/07

    原 英二, 老化細胞の役割とその制御, 第29回 日本Cell Death 学会, 2021/07

    Eiji Hara, High-throughput screening of new compounds that remove senescent cell toward prevention of HCC development, The Asian Pacific Association for the Study of the Liver Conference, 2021/09

    原 英二, 腸内細菌による細胞老化の誘導とその発がん制御における役割 , 千里ライフサイエンスセミナー, 2021/09

    Eiji Hara, Cellular senescence and colorectal cancer: a gut bacterial connection , 第80回日本癌学会シンポジウム, 2021/10

    服部鮎奈, 白血病の悪性化と代謝, 第31回新薬創製談話会, 2021/08

    服部鮎奈, がん細胞のアミノ酸代謝, 第80回日本癌学会学術総会, 2021/10

    高橋 暁子, シンポジウム 「核膜バイオロジー 核膜構造/機能と老化・疾患」「細胞老化による核膜構造変化と加齢性疾患の関わり」, 第126回日本解剖学会総会・全国学術集会/第98回日本生理学会大会 合同大会, 2021/03

    高橋 暁子, YECセミナー 「エクソソーム最前線」「老化細胞が分泌する細胞外小胞の生体機能の解析」, 第94回日本内分泌学会学術総会, 2021/04

    高橋 暁子, 会長企画シンポジウム 「免疫老化・細胞老化の新知見」 「細胞老化とSASPの新知見」, 第21回日本抗加齢医学会総会, 2021/06

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    藤田恭之, 正常上皮細胞と変異細胞間に生じる細胞競合, 2021年度生理研研究会, 2021/09

    藤田恭之, がんの発生から進展における細胞競合, 第80回日本癌学会学術総会, 2021/10

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    篠原正和, 疾患に関わる脂肪酸の「質」:その分子的特性と生理的機能について, 動脈硬化教育フォーラム(日本動脈硬化学会), 2021/02

    浦野泰照, ライブイメージングと最新化学に基づく新たながん医療技術の創製, 消化器領域seminar from Asahikawa, 2021/02

    Akihisa Fukuda, The mechanism of pancreatic cancer development. , The 5th Annual conference of Al-Azhar Hepatogastroenterology club, 2021/08

    片岡圭亮, 先端ゲノム技術を用いたATLの病態解析, 第7回日本HTLV-1学会学術集会, 2021/11

    Toyomasa Katagiri, Yosuke Matsushita, Genetic and epigenetic alterations of SALL3 contributes to chemoresistance in triple-negative breast cancer, ISPCM Annula Meeting online Virtual meeting, 2021/09

    Michiyuki Matsuda, Intercellular communication during collective cell migration, Insights in Signaling Dynamics and Encoding, 2021/06

    Yasuteru Urano, Selective imaging and ablation of target cells with single-cell resolution by novel activatable fluorescence and photosensitizing probes, Pacifichem2021, Opto-bioanalysis: Imaging and controlling biomolecules in live cells (#40) , 2021/12

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    米村重信, Adjusting Tension sensitivity of a-catenin for epithelial morphogenesis., The 51sr NIPS International Symposium, 2021/12

    Eiji Hara, Cellular senescence: Microbial connections, The 6th International Cell Senescence Association Conference, 2021/12

    一條秀憲, 分⼦クラウディングとLLPS による細 の浸 圧センシング, 新学術領域「生命金属科学」領域会議第四回地方巡業(東京), 2021/07

    一條秀憲, PPI阻害を標的とした化合物スクリーニングによる創薬, 第80回日本癌学会, 2021/09

    一條秀憲, 細胞は浸透圧という目に見えないフォースを内側から感じる, 第63回歯科基礎医学会, 2021/10

    一條秀憲, 細胞がストレスを感じる仕組みと疾患〜分子クラウティングとLLPSによる浸透圧センシング〜, 第3回Translational Research Conference for Neuroprotection, 2021/10

    一條秀憲, 細胞は浸透圧という目に見えないフォースを内側から感じる, Science Pioneers Consortium (SPC) 2021, 2021/12

    高橋 暁子, シンポジウム 2S07e 細胞老化の新潮流「Chromatin Dynamics and Inflammatory Gene Expression in Cellular Senescence」, 第94回日本生化学会大会, 2021/11

    久保田 浩行, トランスオミクス解析を用いたマウス肝臓におけるインスリン作用の全体像の理解, 第3回日本メディカルAI学会学術集会, 2021/06

    佐藤俊朗, オルガノイドによるヒト消化器疾患モデル, ゲノム創薬・創発フォーラム, 2021/06

    玉川空樹、川崎慎太郎、川崎健太、藤井正幸、佐藤俊朗, オルガノイド技術が切り拓くヒトがん生物学, 第52回日本膵臓学会大会, 2021/09

    佐藤俊朗, Defining tumor histological evolution using organoid technology, 第80回日本癌学会学術総会, 2021/10

    佐藤俊朗, Modeling human colon cancer stem cells using organoid technology, Barcelona BioMed Conference Stem Cells and Cancer, 2021/10″

  • その他著作物(総説、書籍など)

    Iwasawa K, Takebe T
    Organogenesis in vitro, Current Opinion in Cell Biology, 2021, 73, p.84-91

    Naoko Ohtani and Eiji Hara
    Gut-liver axis-mediated mechanism of liver cancer: A special focus on the role of gut microbiota., Cancer Science, 2021

    Ishihara, S., Ichijo, H., Watanabe, K.
    A novel lens for cell volume regulation: liquid–liquid phase separation., Cell Physiol. Biochem., 2021, vol. 55(No. S1), p.135-160

    Kon, S. and Fujita, Y.
    Cell competition-induced apical elimination of transformed cells, EDAC, orchestrates the cellular homeostasis., Developmental Biology, 2021, 4/20/01, p.112-116

    Maruyama, T. and Fujita, Y.
    Cell competition in vertebrates – a key machinery for tissue homeostasis., Current Opinion in Genetics & Development, 2021, 3/12/00, p.15-21

    丸野貴久, 中西祐貴, 福田晃久, 妹尾浩
    細胞系譜解析とライブイメージングによる膵癌幹細胞の動態の可視化, 実験医学, 202105, vol. 39(No. 8), p.1278-1281

    篠原正和
    メタボロミクス実践ガイド
    実践編③データ解析:GC/MSメタボロミクスのデータ処理プロトコール, 実験医学, 202104, vol.1(No.1), p.179-191

    原 英二
    細胞老化機構を俯瞰する, Geriatric Medicine, 2021, vol.59, p.649-654